TY - JOUR PY - 1994// TI - Does ranitidine affect blood alcohol concentrations? JO - Pharmacotherapy A1 - Pipkin, G. A. A1 - Mills, J. G. A1 - Wood, J. R. SP - 273 EP - 281 VL - 14 IS - 3 N2 - No interaction occurs between ranitidine and alcohol when alcohol 0.3 g/kg or more is taken by either fed or fasted subjects. Ranitidine is associated with small increases (2-4 mg/dl) in blood alcohol concentrations in subjects given alcohol 0.15 g/kg under specific experimental conditions. Mean peak blood alcohol concentrations nevertheless remain low (< 20 mg/dl) after the amount, which is equivalent to about 3 oz of wine or 1 oz of 80-proof liquor. Such changes also occur when alcohol is ingested after different types of foods, and are smaller than the increases when it is drunk on an empty compared with a full stomach. The pharmacokinetic effect seen with ranitidine is without apparent clinical or social significance.

Language: en

LA - en SN - 0277-0008 UR - http://dx.doi.org/ ID - ref1 ER -