TY  - JOUR
PY  - 1993//
TI  - Effects of prior cocaine exposure on subsequent neuronal responsiveness
JO  - Life Sciences
A1  - Nantwi, K. D.
A1  - Schoener, E. P.
SP  - PL327
EP  - 30
VL  - 53
IS  - 19
N2  - In vivo electrophysiological experiments were conducted to examine the responses of single, spontaneously-active neostriatal neurons to repeated cocaine exposure. The second of two administrations in a 30 min interval, attenuated the magnitude and duration of cocaine-induced depression in discharge rate, and enhanced the same variables for cocaine-evoked excitation. These findings indicate that the responsiveness of striatal neurons to cocaine may vary predictably as a function of previous exposure.<p /> <p>Language: en</p> 
LA  - en
SN  - 0024-3205
UR  - http://dx.doi.org/
ID  - ref1
ER  -