TY - JOUR PY - 2010// TI - Acute Toxic Herbal Intake in a Suicide Attempt and Fatal Refractory Ventricular Arrhythmia JO - Basic and Clinical Pharmacology and Toxicology A1 - Strzelecki, Antoine A1 - Pichon, Nicolas A1 - Gaulier, J. M. A1 - Amiel, Jean B. A1 - Champy, Pauline A1 - Clavel, Marc SP - 698 EP - 699 VL - 107 IS - 2 N2 -

This report involves a 54-year-old man who died following refractory ventricular fibrillation after ingestion of a plant in a suicide attempt. Repeated direct-current cardioversions were unsuccessful and no single anti-arrhythmic agent was effective for arrhythmia control. The routine blood toxicological screening was negative. Aconitine, the main toxin of Aconitum napellus was identified using a specific liquid chromatography-tandem mass spectrometry (LC-MS/MS) method. The whole blood concentration (24 mug/l) was higher than those reported in other aconitine-related deaths. The patient had found information about the life-threatening nature of such a toxic herb intake on a free medical encyclopaedia online.

Language: en

LA - en SN - 1742-7835 UR - http://dx.doi.org/10.1111/j.1742-7843.2010.00566.x ID - ref1 ER -