TY  - JOUR
PY  - 1992//
TI  - Cardiotoxicity after accidental herb-induced aconite poisoning
JO  - Lancet
A1  - Tai, Y. T.
A1  - But, P. P.
A1  - Young, K.
A1  - Lau, C. P.
SP  - 1254
EP  - 1256
VL  - 340
IS  - 8830
N2  - Aconitine and its related alkaloids are known cardiotoxins with no therapeutic role in modern western medicine. The rootstocks of Aconitum plants, which contain aconite alkaloids, have been common components of Chinese herbal recipes. We have documented life-threatening intoxication in 17 Chinese subjects after accidental herb-induced aconite poisoning. All patients developed symptoms of aconite toxicity within 2 h of herb ingestion. Most developed tachyarrhythmias, including ventricular tachycardia and fibrillation from which 2 patients died. Toxicological evaluation revealed that aconites from the Aconitum rootstocks were the only plausible casual factor for intoxication. These cases point to the need for strict surveillance of herbal substances with low safety margins.<p />  <p>Language: en</p>
LA  - en
SN  - 0140-6736
UR  - http://dx.doi.org/
ID  - ref1
ER  -