TY - JOUR PY - 2010// TI - The effects of medial temporal lobe resections on verbal threat and fear conditioning JO - Biological psychology A1 - Ahs, Fredrik A1 - Frans, Orjan A1 - Tibblin, Bodil A1 - Kumlien, Eva A1 - Fredrikson, Mats SP - 41 EP - 46 VL - 83 IS - 1 N2 - A left hemisphere advantage in the processing of verbal threat has previously been reported, whereas both hemispheres seem equally important in fear conditioning. Here, we compared the effects of unilateral medial temporal lobe (MTL) resections on verbal threat as well as delay and trace fear conditioning. During verbal threat, right and left MTL-resections attenuated fear potentiated startle in comparison with controls. In contrast to previous studies, MTL-resections did not attenuate delay conditioning of skin conductance responses. Left and right resectioned patients did not differ in psychophysiological responses to verbal threat or delay fear conditioning . Trace conditioning was not observed in any group. Results suggest a bilateral MTL hemispheric involvement in the processing of verbal threat, whereas one intact hemisphere seems sufficient for delay conditioning.
Language: en
LA - en SN - 0301-0511 UR - http://dx.doi.org/10.1016/j.biopsycho.2009.10.002 ID - ref1 ER -