TY - JOUR PY - 1992// TI - Asphyxial deaths from the recreational use of nitrous oxide JO - Journal of forensic sciences A1 - Wagner, S. A. A1 - Clark, Melissa A. A1 - Wesche, D. L. A1 - Doedens, D. J. A1 - Lloyd, A. W. SP - 1008 EP - 1015 VL - 37 IS - 4 N2 - The recreational use of nitrous oxide is widespread. Nitrous oxide for recreational use is usually obtained from anesthesia tanks or whipped-cream machine chargers or cans. Twenty previously described deaths associated with recreational nitrous-oxide use describe anesthesia tanks and whipped-cream machine dispensors as a source. Five deaths associated with nitrous oxide use are presented; two involving whipped-cream cannisters as the source, two involving anesthesia tanks, and one involving a racing fuel tank as a source of nitrous oxide. Autopsy findings in our cases were subtle or negative, but usually suggestive of asphyxia. Through a laboratory simulation, we have confirmed that nitrous oxide displaces oxygen in a closed space, which probably leads to asphyxia. A review of the literature, neuropharmacology, and pathophysiology of nitrous oxide use is also presented.
Language: en
LA - en SN - 0022-1198 UR - http://dx.doi.org/ ID - ref1 ER -