TY  - JOUR
PY  - 1991//
TI  - Aggression, hyperactivity and platelet imipramine binding
JO  - Acta psychiatrica Scandinavica
A1  - Marazziti, Donatella
A1  - Conti, Linda
SP  - 209
EP  - 211
VL  - 84
IS  - 3
N2  - We measured platelet 3H-imipramine binding parameters in 16 subjects affected by different types of mental deficiency, all characterized by hyperactive and/or aggressive behaviour, and in 16 healthy controls. The patients had a lower maximum binding capacity than the controls, with no difference in Kd, irrespectively of the type of mental disorder. These findings suggest a link between 5-HT disturbances, reflected by reduced imipramine binding sites, and behavioural dyscontrol, expressed as hyperactivity and aggression.<p />  <p>Language: en</p>
LA  - en
SN  - 0001-690X
UR  - http://dx.doi.org/
ID  - ref1
ER  -