TY  - JOUR
PY  - 2009//
TI  - Sleep deprivation and Pavlovian fear conditioning
JO  - Learning and memory
A1  - Cai, Denise J.
A1  - Shuman, Tristan
A1  - Harrison, Elizabeth M.
A1  - Sage, Jennifer R.
A1  - Anagnostaras, Stephan G.
SP  - 595
EP  - 599
VL  - 16
IS  - 10
N2  - Sleep has been suggested to play a role in memory consolidation. Prior rodent studies have used sleep deprivation to examine this relationship. First, we reexamined the effects of sleep deprivation on Pavlovian fear conditioning. We found that the deprivation method itself (i.e., gentle handling) induced deficits independent of sleep. Second, we examined an alternative method of sleep deprivation using amphetamine and found that this method failed to induce amnesia. These data indicate that sleep deprivation is a problematic way to examine the role of sleep in memory consolidation, and an alternative paradigm is proposed.<p />  <p>Language: en</p>
LA  - en
SN  - 1072-0502
UR  - http://dx.doi.org/10.1101/lm.1515609
ID  - ref1
ER  -