TY  - JOUR
PY  - 1989//
TI  - Tissue distribution of cocaine in a pregnant woman
JO  - Journal of forensic sciences
A1  - Mittleman, R. E.
A1  - Cofino, J. C.
A1  - Hearn, W. L.
SP  - 481
EP  - 486
VL  - 34
IS  - 2
N2  - Reports of cocaine-related obstetrical problems, including abruptio placentae and spontaneous abortion, have become increasingly evident in the medical literature; however, little is known about tissue distribution of cocaine in the pregnant woman. We report the toxicologic results of distribution studies performed on a pregnant woman and her fetus. Maternal/fetal cocaine concentration ratios were high when comparing blood (9:1), brain (6:5), and kidney (10:6). Possible explanations of the mechanism for lower fetal cocaine concentrations may include uterine vasoconstriction, incomplete maternal/fetal equalibration, or rapid placental/fetal clearance.<p /> <p>Language: en</p> 
LA  - en
SN  - 0022-1198
UR  - http://dx.doi.org/
ID  - ref1
ER  -