TY - JOUR PY - 1986// TI - Acute and chronic toxicity of psychotropic drugs JO - Schweizer Archiv fur Neurologie und Psychiatrie A1 - Bickel, M. H. SP - 106 EP - 109 VL - 137 IS - 5 N2 - Within psychotropic drugs acute toxicity is highest in antidepressants (thymoleptics, MAO-inhibitors, lithium), lower in neuroleptics, and very low in anxiolytics. The order of decreasing chronic toxicity is: neuroleptics, antidepressants, anxiolytics. Each class of psychotropic drugs has a specific toxicological problem. With anxiolytics the major problems stem from their misuse and overuse. With neuroleptics tardive dyskinesia is a serious threat to longterm therapy. Finally, antidepressants are characterized by a low therapeutic index and a resulting high incidence of severe and fatal poisoning cases, both intentional and accidental.

Language: de

LA - de SN - 0258-7661 UR - http://dx.doi.org/ ID - ref1 ER -