TY - JOUR PY - 2005// TI - Suicide, depression, and antidepressants JO - British medical journal: BMJ A1 - Cipriani, Andrea A1 - Barbui, Corrado A1 - Geddes, John R. SP - 373 EP - 374 VL - 330 IS - 7488 N2 - Unipolar depression, one of the most important causes of disability worldwide, is characterised by depressed mood, hopelessness, helplessness, intense feelings of guilt, sadness, low self esteem, thoughts of self harm, and suicide. Up to 15% of patients with unipolar depression eventually commit suicide. Although clinical guidelines recommend treating moderate to severe depression with antidepressant drugs, debate persists on whether some antidepressant drugs, in particular the selective serotonin reuptake inhibitors (SSRIs), cause the emergence or worsening of suicidal ideas in vulnerable patients. LA - SN - 0959-8138 UR - http://dx.doi.org/10.1136/bmj.330.7488.373 ID - ref1 ER -