TY  - JOUR
PY  - 2009//
TI  - Recurrent relapses of depression in a patient established on sertraline after taking herbal medicinal mixtures – a herb–drug interaction?
JO  - Journal of psychopharmacology
A1  - Samaranayake, CN
A1  - Tharangani, PGD
A1  - Prasad, K. P. R. C.
SP  - 216
EP  - 219
VL  - 23
IS  - 2
N2  - We describe a patient with depression who was well controlled with sertraline monotherapy developing two relapses of depression in close temporal relationship with starting ayurvedic herbal mixtures. We discuss the possibility of a pharmacokinetic herb–drug interaction decreasing the therapeutic efficacy of sertraline leading to the relapses of depression. We speculate the herbal plant most likely to be responsible for this interaction is either Terminalia chebula or Commiphora wightii.<p />
LA  - 
SN  - 0269-8811
UR  - http://dx.doi.org/
ID  - ref1
ER  -