TY  - JOUR
PY  - 2008//
TI  - Placebo-controlled, randomized trial of fluoxetine in the treatment of aggression in male intimate partner abusers
JO  - International clinical psychopharmacology
A1  - Lee, Robin
A1  - Kavoussi, R. J.
A1  - Coccaro, E. F.
SP  - 337
EP  - 341
VL  - 23
IS  - 6
N2  - The objective was to determine the efficacy of treating aggressive behavior in men, with a history of intimate partner abuse, with fluoxetine. Twenty-six men with a history of intimate-partner-abusing behavior entered a randomized, placebo-controlled trial of fluoxetine (20-60 mg by mouth per day). The primary outcome measure was the Aggression score from the overt aggression scale-modified (OAS-M). Fluoxetine-treated patients (n=13) did not differ from placebo-treated patients (n=13) on any key demographic or behavioral variables. Although a significant 'pre-post' reduction in OAS-M Aggression score was noted in all patients, no drug-placebo differences for OAS-M Aggression scores were seen in any analysis. Despite the small sample, these results do not support the hypothesis that treatment with an SSRI is associated with a reduction in aggressive behavior among men with a history of intimate partner abuse.<p />  <p>Language: en</p>
LA  - en
SN  - 0268-1315
UR  - http://dx.doi.org/10.1097/YIC.0b013e32830fbdd2
ID  - ref1
ER  -