TY  - JOUR
PY  - 2008//
TI  - Fatal intoxication with milnacipran
JO  - Journal of forensic and legal medicine
A1  - Fanton, Laurent
A1  - Bevalot, Fabien
A1  - Grait, Habdelhamid
A1  - Le Meur, Catherine
A1  - Gaillard, Y.
A1  - Malicier, D.
SP  - 388
EP  - 390
VL  - 15
IS  - 6
N2  - The antidepressant milnacipran is a double serotonin/noradrenalin reuptake inhibitor. The low reported incidence of intoxication indicates excellent tolerance in comparison with tricyclic and second generation antidepressants. We report a fatal intoxication associating milnacipran, at blood levels (femoral=21.5 mg/l, cardiac=20 mg/l) 40-fold higher than the usual treatment concentration, and six other molecules (fluoxetine, norfluoxetine, sertraline, cyamemazine, nordazepam and oxazepam) at therapeutic levels. To the best of our knowledge, this is the first reported fatal intoxication involving milnacipran.<p />  <p>Language: en</p>
LA  - en
SN  - 1752-928X
UR  - http://dx.doi.org/10.1016/j.jflm.2007.12.006
ID  - ref1
ER  -