%0 Journal Article
%T Increased risk of suicidality in patients with psoriasis: a nationwide cohort study in Korea
%J Journal of the European Academy of Dermatology and Venereology
%D 2022
%A Kim, S. M.
%A Ahn, J.
%A Cho, Y. A.
%A Sung, J. Y.
%A Kim, C. Y.
%A Yu, D.
%A Lee, Y. W.
%A Won, S.
%A Choe, Y. B.
%V ePub
%N ePub
%P ePub-ePub
%X BACKGROUND: Psoriasis has a devastating psychological impact on patients' quality of life. However, the relationship between suicidality and psoriasis remains unclear. <br><br>OBJECTIVE: This study analyzed and compared the risk of suicidality (suicidal ideation, suicide attempt, and completed suicide) between patients with psoriasis and the general population. <br><br>METHODS: This nationwide, population-based, retrospective, cohort study analyzed the Korean National Health Insurance Service claim data from 2005 to 2018. <br><br>RESULTS: The study included 348,439 patients with psoriasis aged over 18 years and with age- and sex-matched controls. The risk of suicidality was higher in the psoriasis group than in the control group (adjusted hazard ratio [aHR] 1.21; 95% confidence interval [CI], 1.18-1.24). The aHR of suicidality was higher in the psoriatic arthritis group (aHR, 1.46; 95% CI, 1.39-1.54) than in the psoriasis-alone group (aHR, 1.17; 95% CI, 1.13-1.20). However, the severity of psoriasis and suicidality showed no correlation (mild psoriasis group: aHR, 1.22; 95% CI, 1.18-1.25; moderate-to-severe psoriasis group: aHR, 1.16; 95% CI, 1.10-1.23). <br><br>CONCLUSION: Patients with psoriasis have an increased risk of suicidality. In particular, the presence of arthritis in patients had a more significant effect on the risk of suicidality.<p /> <p>Language: en</p>
%G en
%I John Wiley and Sons
%@ 0926-9959
%U http://dx.doi.org/10.1111/jdv.18565