%0 Journal Article
%T Association of inflammatory bowel disease with suicidal ideation, suicide attempts, and suicide: a systematic review and meta-analysis
%J Journal of psychosomatic research
%D 2022
%A Xiong, Qin
%A Tang, Fuyou
%A Li, Yilin
%A Xie, Fengjiao
%A Yuan, Lei
%A Yao, Chengjiao
%A Wu, Ruike
%A Wang, Juan
%A Wang, Qiuxiang
%A Feng, Peimin
%V 160
%N 
%P e110983-e110983
%X OBJECTIVE: Inflammatory bowel disease (IBD) is associated with psychiatric comorbidities. However, the association between IBD and suicidal ideation or suicide attempts has not been well established. This study aimed to perform a systematic review and meta-analysis to elucidate the relationship between IBD and suicidal ideation, suicide attempts, and suicide. <br><br>METHODS: We systematically searched five electronic databases - PubMed, Embase, CENTRAL, Web of Science, and PsycINFO - from their inception to January 28, 2022. Quality assessment, data synthesis, subgroup analyses, sensitivity analyses, and publication bias assessment were performed on the included studies. <br><br>RESULTS: We identified 28 studies with 1,047,755 patients with IBD. The pooled prevalence of suicidal ideation in patients with IBD was 17.3% (95% CI, 9.5%-25.2%). Patients with IBD were associated with an increased risk of suicide attempts (relative risk [RR], 1.39; 95% CI, 1.08-1.79) and suicide deaths (RR, 1.25; 95% CI, 1.09-1.43) than the controls without IBD. Patients with Crohn's disease subtypes, female IBD, pediatric-onset IBD, young adult IBD, and short-duration IBD had a particularly high risk for suicide. <br><br>CONCLUSION: Patients with IBD had a high prevalence of suicidal ideation and a significantly higher likelihood of suicide attempts and suicide. Caring for patients with IBD, including their mental health needs, may require concerted efforts among gastroenterologists and other healthcare providers.<p /> <p>Language: en</p>
%G en
%I Elsevier Publishing
%@ 0022-3999
%U http://dx.doi.org/10.1016/j.jpsychores.2022.110983