%0 Journal Article
%T Accidents in patients under anticoagulant therapy in the Department of Cardiology at the Yalgado Ouedraogo Teaching Hospital, Ouagadougou (Burkina Faso)
%J Pan African medical journal
%D 2018
%A Millogo, Georges Rosario Christian
%A Kologo, Jonas Koudougou
%A Kinda, Georges
%A Yaméogo, Nobila Valentin
%A Tougma, Jean Baptiste
%A Kambiré, Yibar
%A Thiam, Anna Tall
%A Sanon, Benoît
%A Toguyeni, Jean Yves
%A Samadoulougou, André
%A Zabsonré, Patrice
%V 29
%N 
%P 135-135
%X This study aimed to evaluate the profile of patients hospitalized for anticoagulant-induced hemorrhage. We conducted a retrospective, descriptive study within the Department of Cardiology at the Yalgado Ouedraogo Teaching Hospital, in Ouagadougou, over a period of 2 years from 1 January 2007 to 31 December 2008. All hospitalized patients with anticoagulant-induced hemorrhage were included in the study. The average age of patients was 49,31 ± 17,68 years, the sex-ratio was 2,17. Myocardial infarction was the first indication for anticoagulant treatment, with a rate of 21.05%. Anti vitamin K (AVK) was associated with hemorrhage in 63,16% (n=12) of patients versus 36,84% (n=7) of patients treated with low molecular weight heparins (LMWH); 10 patients had major hemorrhage while nine patients had minor hemorrhage. The average duration of Anti vitamin K (AVK) treatment was 16 ± 58 weeks. Hemorrhage in the digestive tract was the most frequent symptom (31,58%) and, in 89,47% of patients, treatment was associated with platelet aggregation. Treatment of hemorrhagic accident was based on definitive cessation of anticoagulant therapy in 73,68% of patients. Four patients (21.05%) died. The inaccessibility to antidotes such as protamine sulphate and PPSD (Prothrombin, Proconvertine, Stuart factor, and anti-haemophilia B factor) constitutes a real obstacle to adequate treatment for complications; a better education of patients receiving these drugs would be the most important preventive measure, because more than 50% of these accidents are preventable.<p /> <p>Language: fr</p>
%G fr
%I African Field Epidemiology Network
%@ 1937-8688
%U http://dx.doi.org/10.11604/pamj.2018.29.135.10650