%0 Journal Article
%T Gene expression patterns in peripheral blood leukocytes in patients with recurrent ciguatera fish poisoning: preliminary studies
%J Harmful algae
%D 2016
%A Lopez, Maria-Cecilia
%A Ungaro, Ricardo F.
%A Baker, Henry V.
%A Moldawer, Lyle L.
%A Robertson, Alison
%A Abbott, Margaret
%A Roberts, Sparkle M.
%A Grattan, Lynn M.
%A Morris, J. Glenn
%V 57
%N B
%P 35-38
%X Ciguatera fish poisoning (ciguatera) is a common clinical syndrome in areas where there is dependence on tropical reef fish for food. A subset of patients develops recurrent and, in some instances, chronic symptoms, which may result in substantial disability. To identify possible biomarkers for recurrent/chronic disease, and to explore correlations with immune gene expression, peripheral blood leukocyte gene expression in 10 ciguatera patients (7 recurrent, 3 acute) from the U.S. Virgin Islands, and 5 unexposed Florida controls were evaluated. Significant differences in gene expression were noted when comparing ciguatera patients and controls; however, it was not possible to differentiate between patients with acute and recurrent disease, possibly due to the small sample sizes involved.<p /> <p>Language: en</p>
%G en
%I Elsevier Publishing
%@ 1568-9883
%U http://dx.doi.org/10.1016/j.hal.2016.03.009