%0 Journal Article
%T Serotonin in early-onset alcoholism
%J Recent developments in alcoholism
%D 1997
%A Virkkunen, Matti
%A Linnoila, M.
%V 13
%N 
%P 173-189
%X This chapter examines current, common schemes to subgroup alcoholics to arrive at relatively homogeneous groups of patients to facilitate psychobiological and molecular genetic studies. Early-onset, male-limited alcoholism is commonly associated with antisocial personality disorder or antisocial behavioral traits. It is often preceded by early-onset aggressiveness, which is followed by conduct disorder. Early-onset alcoholism among men is associated with low central serotonin turnover rate. The data concerning platelet MAO activity and serotonin uptake to platelets among early-onset alcoholics are conflicting. Recent molecular genetic and brain imaging studies on early-onset alcoholics are preliminary but appear very promising.<p /><p>Language: en</p>
%G en
%I Plenum Press
%@ 0738-422X
%U http://dx.doi.org/