@article{ref1,
title="Sensation-seeking, life events and depression. The Cardiff depression study",
journal="British journal of psychiatry",
year="2001",
author="Farmer, A. and Redman, K. and Harris, T. and Mahmood, Asim and Sadler, S. and McGuffin, P.",
volume="178",
number="",
pages="549-552",
abstract="BACKGROUND: The relationship between adversity and genetic risk factors in depression could be mediated by familial 'hazard prone' traits, as reflected in high levels of sensation-seeking. AIMS: To examine whether high sensation-seeking scores are associated with more adverse life events resulting in depression. METHOD: In a sib-pair design, 108 probands with depression and their siblings and 105 healthy control subjects and their siblings were compared for psychopathology, life events and scores on the Sensation-Seeking Questionnaire (SSQ). RESULTS: The SSQ scores were correlated negatively with depression, were familial and were correlated positively with less severe events, but not the severe events typically associated with depressive onsets. CONCLUSIONS: The SSQ measures a familial personality trait and depression is associated with lower scores. Although high sensation-seeking is associated with a higher rate of life events, these carry little threat.<p /> <p>Language: en</p>",
language="en",
issn="0007-1250",
doi="",
url="http://dx.doi.org/"
}