@article{ref1,
title="Timing Variability during Gait Initiation Is Increased in People with Alzheimer's Disease Compared to Controls",
journal="Dementia and geriatric cognitive disorders",
year="2008",
author="Wittwer, Joanne E. and Andrews, Peta T. and Webster, Kate E. and Menz, Hylton B.",
volume="26",
number="3",
pages="277-283",
abstract="Background/Aims: Variability of constant speed walking is closely related to falls risk in people with Alzheimer's disease (AD) who fall at 3 times the rate of normal elders. Falls are likely to be provoked during gait initiation, so this study aimed to determine if people with mild-moderate AD have greater variability of gait at initiation. Methods: Measures of step and stride length and time, step width and double support time were recorded during gait initiation for 10 males and 10 females with AD and 20 age- and gender-matched controls. Variability was calculated using the coefficient of variation (CV). Effect size was calculated using Cohen's d. Results: During gait initiation AD participants had greater variability than controls in stride timing (AD CV = 4.65, Control CV = 3.64; p<0.05, d = 0.71) and double support proportion (AD CV = 9.40, Control CV = 7.62; p<0.05, d = 0.8). Conclusion: Increased timing variability in people with AD occurs during gait initiation as well as during constant speed walking and is evident in the early disease stages.<p /><p>Language: en</p>",
language="en",
issn="1420-8008",
doi="10.1159/000160961",
url="http://dx.doi.org/10.1159/000160961"
}