@article{ref1,
title="Antidepressant treatment is associated with a reduction in suicidal ideation and suicide attempts",
journal="Acta psychiatrica Scandinavica",
year="2008",
author="Mulder, Roger T. and Joyce, P. R. and Frampton, Christopher M. A. and Luty, Suzanne E.",
volume="118",
number="2",
pages="116 - 122",
abstract="Objective: To measure changes in suicidal behaviours during 6 months of treatment with antidepressants. Method: A group of depressed patients (n = 195) were assessed for suicidal behaviours in the 6 months prior to treatment. They were prospectively assessed for suicidal behaviours during 6 months of treatment with antidepressants. Results: Patients who made suicide attempts fell from 39 in the 6 months prior to treatment to 20 during treatment. Significant suicidal ideation reduced from 47% at baseline to 14% at 3 weeks remaining below this during the rest of the treatment. Twenty patients had emergent suicidal ideation; five of them had not experienced some level of suicidal behaviour in the 6 months prior to treatment. Conclusion: Suicide behaviours are common in depressed out-patients. Antidepressant treatment is associated with a rapid and significant reduction in suicidal behaviours. The rate of emergent suicidal behaviour was low and the risk benefit ratio for antidepressants appears to favour their use.<p>Language: en</p>",
language="en",
issn="0001-690X",
doi="10.1111/j.1600-0447.2008.01179.x",
url="http://dx.doi.org/10.1111/j.1600-0447.2008.01179.x"
}