@article{ref1,
title="The clinical correlates of suicidal ideation in Parkinson's disease",
journal="Parkinsonism and related disorders",
year="2019",
author="Belvisi, Daniele and Berardelli, Isabella and Ferrazzano, Gina and Costanzo, Matteo and Corigliano, Valentina and Fabbrini, Giovanni and Berardelli, Alfredo and Pompili, Maurizio",
volume="63",
number="",
pages="54-59",
abstract="INTRODUCTION: Suicidal ideation is increased in Parkinson's disease (PD) patients. The possible relationship between parkinsonian motor and non-motor symptoms and suicidal ideation in PD is unknown. The aim of the study was to evaluate suicidal ideation in patients with PD in a controlled study specifically designed to identify the clinical correlates of PD suicidal ideation. METHODS: We consecutively enrolled 100 patients with PD, 76 patients with psoriasis and 80 healthy subjects. Motor symptoms and complications were evaluated by using the International Parkinson and Movement Disorder Society-Unified Parkinson's Disease Rating Scale. Non-motor symptoms were evaluated by means of the Non-Motor Symptoms assessment scale for PD. All patients also underwent a psychiatric evaluation that included the administration of the Columbia-Suicide Severity Rating Scale. RESULTS: Suicidal ideation was present in 31% of PD patients, 16% of patients with psoriasis and 2% of healthy controls. PD patients showing suicidal ideation have more frequent motor complications, more severe non-motor symptoms and a higher perceived disability than patients without suicidal ideation. Suicidal ideation correlated with the presence of motor complications as well as with non-motor symptom severity, perceived disability severity and the presence of psychiatric disorders. CONCLUSIONS: Our findings showed that suicidal ideation is increased in PD patients compared with healthy controls and patients with psoriasis and that several clinical PD features, including motor complications and non-motor symptoms, are associated with suicidal ideation in PD. The results suggest a multi-factorial origin of PD suicidal ideation.<p /><p>Language: en</p>",
language="en",
issn="1353-8020",
doi="10.1016/j.parkreldis.2019.02.047",
url="http://dx.doi.org/10.1016/j.parkreldis.2019.02.047"
}