
@article{ref1,
title="Survival after a massive overdose of arsenic trioxide",
journal="Critical care and resuscitation",
year="2009",
author="Kim, Lawrence H. C. and Abel, Simon J. C.",
volume="11",
number="1",
pages="42-45",
abstract="Arsenic poisoning remains a therapeutic challenge, and outcomes are often poor. An 18-year-old man deliberately ingested termiticide containing a massive dose of arsenic trioxide. Arsenic concentration was 6.3 micromol/L in serum on ICU Day 1, and 253 micromol/L in the first 24-hour urine sample, with a urinary arsenic/creatinine ratio of 84 200 micromol/mol. He was treated with the chelating agent meso-2,3-dimercaptosuccinic acid (DMSA) (replaced by dimercaprol on Days 2-5) and required intensive support for multisystem organ failure, but recovered slowly. Nine weeks after the ingestion the only ongoing clinical issue was persistent but slowly improving peripheral neuropathy.<p /><p>Language: en</p>",
language="en",
issn="1441-2772",
doi="",
url="http://dx.doi.org/"
}