
@article{ref1,
title="Neuroprotective aspects of a novel MAO-B inhibitor PF9601N",
journal="Neurobiology (Budapest, Hungary)",
year="2000",
author="Perez, V. and Morón, J. and Pastó, M. and Unzeta, M.",
volume="8",
number="3-4",
pages="231-236",
abstract="PF9601N is an acetylenic tryptamine derivative devoid of amphetamine-like properties, that behaves as suicide MAO-B inhibitor more potent than l-deprenyl. It is highly selective towards MAO-B and it neuroprotects from the neurotoxicity induced in C57Bl/6 adult mice by 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP). PF9601N also shows in vitro antioxidant properties by inhibiting the dopamine autoxidation. A potential therapeutic use in Parkinson's disease treatment is proposed for this compound.<p /><p>Language: en</p>",
language="en",
issn="1216-8068",
doi="",
url="http://dx.doi.org/"
}