
@article{ref1,
title="Cholesterol and serotonin indices in depressed and suicidal patients",
journal="Journal of affective disorders",
year="2001",
author="Sarchiapone, M. and Camardese, G. and Roy, A. and Della Casa, S. and Satta, M. A. and Gonzalez, B. and Berman, J. and De Risio, S.",
volume="62",
number="3",
pages="217-219",
abstract="BACKGROUND: Prolactin and cortisol responses to d-fenfluramine challenge of central serotonin are reduced in depressed and suicidal patients. Low serum cholesterol levels are also reported in suicidal behavior. Thus, we examined for a relationship between serum cholesterol and fenfluramine challenge responses in patients with depression and/or attempted suicide. METHODS: We studied 12 patients and six controls. Blood was drawn for baseline serum cholesterol and the d-fenfluramine challenge test performed. RESULTS: Serum cholesterol levels were significantly lower in suicidal patients than in either non-suicidal patients or controls. However, neither the prolactin nor cortisol responses to d-fenfluramine correlated significantly with serum cholesterol levels. CONCLUSION: No relationship was found between serum cholesterol and these peripheral indices of serotonergic function.<p /><p>Language: en</p>",
language="en",
issn="0165-0327",
doi="10.1016/s0165-0327(99)00200-1",
url="http://dx.doi.org/10.1016/s0165-0327(99)00200-1"
}