@article{ref1,
title="An association between low levels of 5-HIAA and HVA in cerebrospinal fluid and early mortality in a diagnostically mixed psychiatric sample",
journal="British journal of psychiatry",
year="1993",
author="Faustman, W. O. and Ringo, D. L. and Faull, K. F.",
volume="163",
number="",
pages="519-521",
abstract="We followed up a sample of psychiatric patients (diagnoses predominantly schizophrenia and depression) who had participated in in-patient studies of their CSF over the past 15 years. The status of 73 former patients was confirmed, of whom 12 had died. Seven of these patients died at age < or = 40, largely of suicide, homicide, or accidental causes. These seven patients had significantly lower CSF 5-HIAA and HVA than living control patients. There were significant direct correlations between age at death and both CSF 5-HIAA and HVA in the deceased patients. The results offer support for CSF monoamine metabolites relating to early death in a diagnostically diverse sample of psychiatric patients.<p /><p>Language: en</p>",
language="en",
issn="0007-1250",
doi="10.1192/bjp.163.4.519",
url="http://dx.doi.org/10.1192/bjp.163.4.519"
}