@article{ref1,
title="Changes in the level of biogenic amines in cerebrospinal fluid of suicidal attempt cases",
journal="Indian journal of clinical biochemistry",
year="1995",
author="Husain, K. and Sahu, R.N. and Rahman, R. and Nair, A.",
volume="10",
number="1",
pages="45-47",
abstract="The levels of norepinephrine (NE), dopamine (DA) serotonin (5-HT) and its metabolite 5-hydroxyindole acetic acid (5-HIAA) have been determined in the cerebrospinal fluid (CSF) of normal (n=25) and suicidal attempt cases (n=30). A significant decrease in the level of NE (p<0.01), 5-HT(p<0.001) and 5-HIAA (p<0.001) in the CSF of suicide attempt cases were observed as compared to normal controls. It is concluded that CSF 5-HIAA level which is drastically depleted may be used as an early biochemical indicator of suicidal attempt so that it may be treated by the drugs which can enhance the suppressed neurotransmitter activity. © 1995 Association of Clinical Biochemists of India.<p /><p>Language: en</p>",
language="en",
issn="0970-1915",
doi="10.1007/BF02873669",
url="http://dx.doi.org/10.1007/BF02873669"
}