@article{ref1,
title="Two cases of fatal methemoglobinemia caused by self-poisoning with sodium nitrite: A case report",
journal="Medicine (Baltimore)",
year="2022",
author="Mun, Sung Hoon and Park, Gwan Jin and Lee, Ji Han and Kim, Young Min and Chai, Hyun Seok and Kim, Sang Chul",
volume="101",
number="7",
pages="e28810-e28810",
abstract="RATIONALE: Sodium nitrite intoxication reportedly causes severe methemoglobinemia. Recent studies reported that most clinically significant cases resulted from intentional exposure in suicidal attempts. We describe 2 cases of severe methemoglobinemia secondary to intentional sodium nitrite intoxication in suicidal attempts. PATIENTS CONCERNS: A 26-year-old man and 20-year-old woman attempted suicide by taking sodium nitrite, and were brought to the emergency department. DIAGNOSIS: The male patient collapsed at the scene. He ingested approximately 18 g of sodium nitrate, and his methemoglobin level was 90.3%. The female patient was conscious, but was cyanotic. She ingested approximately 12.5 g of sodium nitrite, and her methemoglobin level was 54.6%. INTERVENTIONS: The male patient received advanced cardiac life support in the emergency department. Methylene blue was immediately administered for the female patient. OUTCOMES: The male patient died despite aggressive resuscitation. The female patient's cyanosis resolved, and her methemoglobin level decreased to 1.2% 3 hours later. LESSONS: The immediate administration of methylene blue in severe methemoglobinemia patients prevented fatal consequences. The public should be informed about the accessibility and toxicity of sodium nitrite.<p /><p>Language: en</p>",
language="en",
issn="0025-7974",
doi="10.1097/MD.0000000000028810",
url="http://dx.doi.org/10.1097/MD.0000000000028810"
}