@article{ref1,
title="Research Progress in Cell Apoptosis Induced by Shikonin and Signal Pathway of Apoptosis",
journal="Chinese Journal of Information on Traditional Chinese Medicine",
year="2017",
author="Xie, Yu and Hou, Xiaolong and Wu, Chunlian",
volume="",
number="12",
pages="125-129",
abstract="s:Apoptosis, also known as programmed cell death, is a gene controlled active cell suicide process in order to maintain balance of organisms. Apoptosis is mainly mediated through three signal pathways, including the endoplasmic reticulum, mitochondria, and death receptor. As a kind of naphthoquinone compounds and one of the main active ingredients of Lithospermum, shikonin has many biological activities, and its anti-cancer research is recent hot spot. The anti-cancer mechanism of shikonin is closely related with apoptosis and three kinds of signaling pathways. This article reviewed the research progress in apoptosis and signal pathways induced by shikonin.<p /><p>Language: zh</p>",
language="zh",
issn="1005-5304",
doi="10.3969/j.issn.1005-5304.2017.03.031",
url="http://dx.doi.org/10.3969/j.issn.1005-5304.2017.03.031"
}