@article{ref1,
title="The RECOVER program: Disability risk groups and 1-year outcome after 7 or more days of mechanical ventilation",
journal="American journal of respiratory and critical care medicine",
year="2016",
author="Herridge, M.S. and Chu, L.M. and Matte, A. and Tomlinson, G. and Chan, L. and Thomas, C. and Friedrich, J.O. and Mehta, S. and Lamontagne, F. and Levasseur, M. and Ferguson, N.D. and Adhikari, N.K.J. and Rudkowski, J.C. and Meggison, H. and Skrobik, Y. and Flannery, J. and Bayley, M. and Batt, J. and Dos Santos, C. and Abbey, S.E. and Tan, A. and Lo, V. and Mathur, S. and Parotto, M. and Morris, D. and Flockhart, L. and Fan, E. and Lee, C.M. and Wilcox, M.E. and Ayas, N. and Choong, K. and Fowler, R. and Scales, D.C. and Sinuff, T. and Cuthbertson, B.H. and Rose, L. and Robles, P. and Burns, S. and Cypel, M. and Singer, L. and Chaparro, C. and Chow, C.-w. and Keshavjee, S. and Brochard, L. and Hebert, P. and Slutsky, A.S. and Marshall, J.C. and Cook, D. and Cameron, J.I.",
volume="194",
number="7",
pages="831-844",
abstract="Rationale: Disability risk groups and 1-year outcomeafter greater than or equal to 7 days of mechanical ventilation (MV) in medical/surgical intensive care unit (ICU) patients are unknown and may inform education, prognostication, rehabilitation, and study design. <br><br>OBJECTIVES: To stratify patients for post-ICU disability and recovery to 1 year after critical illness. <br><br>METHODS:Weevaluated a multicenter cohort of 391 medical/surgical ICU patients who received greater than or equal to 1 week of MV at 7 days and 3, 6, and 12 months after ICU discharge. Disability risk groups were identified using recursive partitioning modeling. Measurements and Main Results: The 7-day post-ICU Functional Independence Measure (FIM) determined the recovery trajectory to 1-year after ICU discharge and was an independent risk factor for 1-year mortality. The 7-day post-ICU FIM was predicted by age and ICU length of stay. By 2 weeks of MV, ICU patients could be stratified into four disability groups characterized by increasing risk for post ICU disability, ICU and post-ICU healthcare use, and disposition. Patients less than 42 years with ICU length of stay less than 2 weeks had the best function and fewest deaths at 1 year compared with patients greater than 66 years with ICU length of stay greater than 2 weeks who sustained the worst disability and 40% 1-year mortality. Depressive symptoms (17%) and post-traumatic stress disorder (18%) persisted at 1 year. <br><br>CONCLUSIONS: ICU survivors of greater than or equal to 1 week of MVmay be stratified into four disability groups based on age and ICU length of stay. These groups determine 1-year recovery and healthcare use and are independent of admitting diagnosis and illness severity. Copyright © 2016 by the American Thoracic Society.<p /><p>Language: en</p>",
language="en",
issn="1073-449X",
doi="10.1164/rccm.201512-2343OC",
url="http://dx.doi.org/10.1164/rccm.201512-2343OC"
}