@article{ref1,
title="Time-course profile of urinary excretion of intravenously administered α-pyrrolidinovalerophenone and α-pyrrolidinobutiophenone in a human",
journal="Forensic toxicology",
year="2014",
author="Namera, A. and Konuma, K. and Kawamura, M. and Saito, T. and Nakamoto, A. and Yahata, M. and Ohta, S. and Miyazaki, S. and Shiraishi, H. and Nagao, M.",
volume="32",
number="1",
pages="68-74",
abstract="We report the time-course profile of urinary excretion of α-pyrrolidinovalerophenone (α-PVP) and α- pyrrolidinobutiophenone (α-PBP) after intravenous injection in a human. The subject was a man aged in his forties, who intravenously injected unknown amounts of so-called unregulated drugs with the intention to commit suicide. The urinary concentrations of the drugs were analyzed by MonoSpin® extraction and gas chromatography-mass spectrometry. α-PVP, α-PBP, and their 2′-oxo metabolites of these compounds were identified in the urine. The highest concentration of α-PVP and α-PBP in urine was 1.2 and 1.6 μg/ml, respectively. The excretion half-lives of α-PVP and α-PBP were calculated to be 22 and 11 h, respectively. To our knowledge, this is the first report on the urinary excretion profiles of α-PVP and α-PBP in a human. © 2013 Japanese Association of Forensic Toxicology and Springer Japan.<p /><p>Language: en</p>",
language="en",
issn="1860-8965",
doi="10.1007/s11419-013-0203-8",
url="http://dx.doi.org/10.1007/s11419-013-0203-8"
}