@article{ref1,
title="Oral isotretinoin is first-line treatment in severe nodular acne, with other agents indicated as second-line or adjunctive therapy",
journal="Drugs and therapy perspectives",
year="2011",
author="",
volume="27",
number="8",
pages="11-14",
abstract="Oral isotretinoin is the first-line treatment option for severe nodular acne. If isotretinoin is contraindicated or poorly tolerated, combination therapy with an oral antibacterial, benzoyl peroxide and a topical retinoid is recommended. Other options include oral anti-androgens and corticosteroids. © 2011 Adis Data Information BV. All rights reserved.<p /><p>Language: en</p>",
language="en",
issn="1172-0360",
doi="10.2165/11207860-000000000-00000",
url="http://dx.doi.org/10.2165/11207860-000000000-00000"
}