@article{ref1,
title="Three cases of chemical burns caused due to dimethyl sulfate poisoning",
journal="Curēus",
year="2024",
author="Mizuta, Shiori and Miyakoshi, Tatsuya and Matsui, Kotaro and Nakayama, Yuko and Koshida, Yosinao",
volume="16",
number="3",
pages="e57060-e57060",
abstract="Dimethyl sulfate (DMS) is a drug widely used as a pharmaceutical and synthetic raw material. On the other hand, it is highly toxic and requires management and treatment as a hazardous substance. A mass outbreak of chemical burns resulting from DMS poisoning occurred at a drug factory. All three patients were brought to our hospital, a tertiary emergency medical facility, several hours after exposure. Their vital signs were stable, with only eye pain and a sore throat. However, after admission, two patients required emergency tracheostomy or endotracheal intubation due to laryngeal edema. Improvement was achieved through the administration of steroids, but a severely injured patient required an extended treatment period. DMS poisoning is rare; however, it can be fatal depending on the exposure concentration. Furthermore, even if the initial symptoms are mild, laryngeal edema may develop later, requiring careful monitoring and appropriate airway interventions.<p /> <p>Language: en</p>",
language="en",
issn="2168-8184",
doi="10.7759/cureus.57060",
url="http://dx.doi.org/10.7759/cureus.57060"
}