@article{ref1,
title="Traumatic brain injury research: homogenising heterogeneity",
journal="Lancet neurology",
year="2023",
author="Rubiano, Andrés M. and Lee, Kiwon",
volume="22",
number="11",
pages="973-975",
abstract="Traumatic brain injury is a heterogeneous condition, and subgroups of patients with different patterns of injury, severity, and outcomes have been identified. 1 This heterogeneity can limit the ability of clinical studies to show a benefit of management strategies, which might be efficacious in only a subset of patients. Measurement of intracranial pressure and brain oxygen tissue pressure (PbtO2) can help to identify a secondary injury after traumatic brain injury in a potentially reversible stage. Thus, a dual-monitoring approach has been suggested as an important decision-making strategy during early critical care of these patients. A feasibility trial has shown that the dual system can help to reduce brain tissue hypoxia.<p /> <p>Language: en</p>",
language="en",
issn="1474-4422",
doi="10.1016/S1474-4422(23)00325-3",
url="http://dx.doi.org/10.1016/S1474-4422(23)00325-3"
}