@article{ref1,
title="Association of vitamin D deficiency with anxiety and depressive symptoms among middle school students in Shenzhen",
journal="Chinese journal of school health",
year="2023",
author="Mengya, Zhao and Shaojun, X. U. and Xiaoheng, L. I. and Huiqiong, X. U. and Dingyan, Chen and Yi, Z. H. U. and Fangbiao, T. a. O.",
volume="44",
number="7",
pages="1030-1033",
abstract="<sec>  <b>Objective</b>  To explore the association of vitamin D deficiency with anxiety and depressive symptoms as well as their comorbidity, so as to provide references for improving the mental health of children and adolescents.</sec><sec>  <b>Methods</b>  From October to December 2021, a total of 1 323 students from four middle schools in Shenzhen were selected by using convenience sampling method for a questionnaire survey and physical examination. Fasting blood samples were collected to detect vitamin D levels. The <i>Chi</i>-square test and multiple Logistic regression model were used to analyze the association of vitamin D deficiency with anxiety and depressive symptoms and their comorbidity among middle school students.</sec><sec>  <b>Results</b>  The detection rates of anxiety, depressive, and thier comorbidities in middle school students were 33.0%, 21.5% and 16.3%, respectively. After adjusting for confounding factors, vitamin D deficiency was positively associated with the risk of anxiety symptoms (<i>OR</i>=1.59, 95%<i>CI</i>=1.02-2.46), depressive symptoms (<i>OR</i>=1.94, 95%<i>CI</i>=1.22-3.09) and anxiety-depressive co-morbid symptoms (<i>OR</i>=1.75, 95%<i>CI</i>=1.06-2.90) in secondary school students (<i>P</i> < 0.05).</sec><sec>  <b>Conclusion</b>  Vitamin D deficiency is associated with an increased risk of anxiety, depressive and their co-morbidity symptoms in middle school students, and the directionality of the association should be further studied.</sec><p /> <p>Language: zh</p>",
language="zh",
issn="1000-9817",
doi="10.16835/j.cnki.1000-9817.2023.07.016",
url="http://dx.doi.org/10.16835/j.cnki.1000-9817.2023.07.016"
}