@article{ref1,
title="Non-invasive and label-free on-chip impedance monitoring of heatstroke",
journal="Biosensors (Basel)",
year="2023",
author="Zhao, Yueli and Fan, Weihua and Liu, Anwei and Pan, Shihua and Xu, Chongxiao and Peng, Hailun and Yin, Bingling and Wang, Xiaodong and Dong, Jianhua and Pan, Zhiguo",
volume="13",
number="7",
pages="-",
abstract="Heatstroke (HS) is a life-threatening injury requiring neurocritical care which could lead to central nervous system dysfunction and severe multiple organ failure syndrome. The cell-cell adhesion and cell permeability are two key factors for characterizing HS. To investigate the process of HS, a biochip-based electrical model was proposed and applied to HS. During the process, the value of TEER is associated with cell permeability and C(I) which represents cell-cell adhesion decreases that are consistent with the reduction in cell-cell adhesion and cell permeability characterized by proteins (occludin, VE-Cadherin and ZO-1) and RNA level. The results imply that the model can be used to monitor the biological process and other biomedical applications.<p /> <p>Language: en</p>",
language="en",
issn="2079-6374",
doi="10.3390/bios13070686",
url="http://dx.doi.org/10.3390/bios13070686"
}