@article{ref1,
title="Age-related variations of genetic and environmental contributions to the covariation of fear, distress and externalizing symptoms: a twin study in childhood and adolescence",
journal="Child psychiatry and human development",
year="2023",
author="De Francesco, Stefano and Scaini, Simona and Alessandri, Guido and Medda, Emanuela and Camoni, Laura and Stazi, Maria Antonietta and Fagnani, Corrado",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="The frequency with which Internalizing and Externalizing symptoms co-occur suggests that, behind both domains, there may be a common susceptibility represented by a general psychopathology factor. However, it's still unclear whether this common susceptibility is affected by age-related variations. Internalizing (i.e., Fear and Distress) and Externalizing symptoms were evaluated in 803 twin pairs from the population-based Italian Twin Registry. Model-fitting analysis was performed separately in the 6-14 and 15-18 age groups to estimate genetic and environmental contributions to the covariance among symptoms. For the 6-14 group, a multivariate Cholesky model best fitted the data, while, for the 15-18 group, the best fit was provided by a Common Pathway model in which nearly 50% of total variance of each trait was mediated by common genetic factors. Our findings support a common susceptibility behind Internalizing and Externalizing symptoms, mainly genetic in origin, that becomes more evident at the beginning of puberty.<p /> <p>Language: en</p>",
language="en",
issn="0009-398X",
doi="10.1007/s10578-023-01498-w",
url="http://dx.doi.org/10.1007/s10578-023-01498-w"
}