@article{ref1,
title="Exposures and suspected intoxications to pharmacological and non-pharmacological agents in children aged 0-14 years: real-world data from an Italian reference poison control centre",
journal="Journal of clinical medicine",
year="2023",
author="Brilli, Valentina and Crescioli, Giada and Missanelli, Andrea and Lanzi, Cecilia and Trombini, Massimo and Ieri, Alessandra and Gambassi, Francesco and Vannacci, Alfredo and Mannaioni, Guido and Lombardi, Niccolò",
volume="12",
number="1",
pages="e352-e352",
abstract="This study describes the exposures and suspected intoxications in children (0-14 years) managed by an Italian reference poison control center (PCC). A seven-year observational retrospective study was performed on the medical records of the Toxicology Unit and PCC, Careggi University Hospital, Florence (Italy). During the study period (2015-2021), a total of 27,212 phone call consultations were managed by the PCC, of which 11,996 (44%) involved subjects aged 0-14 years. Most cases occurred in males (54%) aged 1-5 years (73.8%), mainly at home (97.4%), and with an oral route of intoxication (93%). Cases mainly occurred involuntarily. Consultations were generally requested by caregivers; however, in the age group 12-14 years, 70% were requested by healthcare professionals due to voluntary intoxications. Cleaners (19.44%) and household products (10.90%) were the most represented suspected agents. Pharmacological agents accounted for 28.80% of exposures. Covariates associated with a higher risk of emergency department visit or hospitalization were voluntary intoxication (OR 29.18 [11.76-72.38]), inhalation route (OR 1.87 [1.09-3.23]), and pharmacological agents (OR 1.34 [1.23-1.46]), particularly central nervous system medications. Overall, consultations do not burden national and regional healthcare facilities, revealing the activity of PCCs as having a strategic role in reducing public health spending, even during the COVID-19 pandemic.<p /> <p>Language: en</p>",
language="en",
issn="2077-0383",
doi="10.3390/jcm12010352",
url="http://dx.doi.org/10.3390/jcm12010352"
}