@article{ref1,
title="Dimethoate self-poisoning-induced severe hypotension",
journal="Current medical issues (Vellore)",
year="2022",
author="Tiwari, Anand and Zirpe, Kapil and Wadia, Rustom and Gurav, Sushma and Deshmukh, Abhijit",
volume="20",
number="3",
pages="187-190",
abstract="Intentional ingestion of organophosphorus compound (OP) poisoning continues to be a frequent reason for critical care admission in India. For the past 6 decades, the OP compounds used in India for the poisoning had effects on cholinergic and neurogenic fibers producing the respiratory and neurologic presentation. Recently, a less frequent OP poison has appeared which acts on cardiac sympathetic fibers with bradycardia and hypotension as presenting features. The shock which was nonresponsive to dopamine/dobutamine was identified as a major cause of death in patients with dimethoate poisoning in a large prospective cohort study. Severe dimethoate poisoning in contrast to other OP compounds has a high case fatality rate. There have been case reports from outside India. We report the first two cases with successful treatment of this toxicity in India.<p /> <p>Language: en</p>",
language="en",
issn="0973-4651",
doi="10.4103/cmi.cmi_12_22",
url="http://dx.doi.org/10.4103/cmi.cmi_12_22"
}