@article{ref1,
title="Association of inflammatory bowel disease with suicidal ideation, suicide attempts, and suicide: a systematic review and meta-analysis",
journal="Journal of psychosomatic research",
year="2022",
author="Xiong, Qin and Tang, Fuyou and Li, Yilin and Xie, Fengjiao and Yuan, Lei and Yao, Chengjiao and Wu, Ruike and Wang, Juan and Wang, Qiuxiang and Feng, Peimin",
volume="160",
number="",
pages="e110983-e110983",
abstract="OBJECTIVE: Inflammatory bowel disease (IBD) is associated with psychiatric comorbidities. However, the association between IBD and suicidal ideation or suicide attempts has not been well established. This study aimed to perform a systematic review and meta-analysis to elucidate the relationship between IBD and suicidal ideation, suicide attempts, and suicide. <br><br>METHODS: We systematically searched five electronic databases - PubMed, Embase, CENTRAL, Web of Science, and PsycINFO - from their inception to January 28, 2022. Quality assessment, data synthesis, subgroup analyses, sensitivity analyses, and publication bias assessment were performed on the included studies. <br><br>RESULTS: We identified 28 studies with 1,047,755 patients with IBD. The pooled prevalence of suicidal ideation in patients with IBD was 17.3% (95% CI, 9.5%-25.2%). Patients with IBD were associated with an increased risk of suicide attempts (relative risk [RR], 1.39; 95% CI, 1.08-1.79) and suicide deaths (RR, 1.25; 95% CI, 1.09-1.43) than the controls without IBD. Patients with Crohn's disease subtypes, female IBD, pediatric-onset IBD, young adult IBD, and short-duration IBD had a particularly high risk for suicide. <br><br>CONCLUSION: Patients with IBD had a high prevalence of suicidal ideation and a significantly higher likelihood of suicide attempts and suicide. Caring for patients with IBD, including their mental health needs, may require concerted efforts among gastroenterologists and other healthcare providers.<p /> <p>Language: en</p>",
language="en",
issn="0022-3999",
doi="10.1016/j.jpsychores.2022.110983",
url="http://dx.doi.org/10.1016/j.jpsychores.2022.110983"
}