@article{ref1,
title="Morbidity and associated factors of depressive disorder in patients with Parkinson's disease",
journal="Journal of nervous and mental disease",
year="2022",
author="Lee, Yu and Chiou, Yu-Jie and Chang, Yung-Yee and Hung, Chi-Fa and Chen, Ying-Fa and Lin, Tsu-Kung and Wang, Liang-Jen",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="Parkinson's disease (PD) is a progressive, neurodegenerative disorder and is commonly comorbid with depression. The aim of this cross-sectional study was to assess morbidity and associated factors of depression in patients with PD. In total, 181 patients with PD were enrolled and assessed using the Mini-International Neuropsychiatric Interview. Of the sample, 51% had at least one psychiatric diagnosis. The most prevalent psychiatric disorder was depressive disorder (27.6%), followed by rapid eye movement sleep behavior disorder (9.9%), insomnia disorder (8.8%), and adjustment disorder (2.8%). Severity of anxiety, suicide risk, and anxiolytics/hypnotics use were factors associated with depressive disorder in PD patients. Furthermore, severity of anxiety was significantly linked with suicide risk. We suggest that use of a standardized structured interview for early detection of depression in PD patients is crucial. Anxiety, anxiolytics/hypnotics use, depression, and suicide risks are interrelated and warrant clinical concerns regarding PD patients.<p /> <p>Language: en</p>",
language="en",
issn="0022-3018",
doi="10.1097/NMD.0000000000001537",
url="http://dx.doi.org/10.1097/NMD.0000000000001537"
}