@article{ref1,
title="Fatal pulmonary Scedosporium aurantiacum infection in a patient after near-drowning: a case report",
journal="Current Medical Mycology",
year="2021",
author="Ghasemian, Roya and Bandegani, Azadeh and Kermani, Firoozeh and Faeli, Leila and Roohi, Behrad and Yosefi Abdolmaleki, Elham and Hedayati, Mohammad T. and Roilides, Emmanuel and Shokohi, Tahereh",
volume="7",
number="4",
pages="38-42",
abstract="Background and Purpose: Scedosporium spp. is a saprophytic fungus that may cause invasive pulmonary infection due to the aspiration of contaminated water in both immunosuppressed and immunocompetent hosts.Case report: Herein, we report a fatal case of pulmonary infection caused by Scedosporium species associated with a car crash and near-drowning in a sewage canal.Scedosporium aurantiacum isolated from bronchoalveolar lavage was identified by PCR-sequencing of β-tubulin genes. The minimum inhibitory concentration values for amphotericin B, itraconazole, posaconazole, isavuconazole were >16 µg/ml, and >8 µg/ml for anidulafungin, micafungin, and caspofungin. Voriconazole was found to be the most active agent with a MIC of 1 µg/ml.<br><br>CONCLUSION: This report, as the first case of pulmonary scedosporiosis after near-drowningin Iran, highlights the importance of high suspicion in near-drowning victims, promptidentification of Scedosporium spp., and early initiation of appropriate antifungal therapy.<p /> <p>Language: en</p>",
language="en",
issn="2423-3439",
doi="10.18502/cmm.7.4.8410",
url="http://dx.doi.org/10.18502/cmm.7.4.8410"
}