@article{ref1,
title="Medication review in preventing older adults' fall-related injury: a systematic review & meta-analysis",
journal="Canadian geriatrics journal",
year="2021",
author="Ming, Yu and Zecevic, Aleksandra A. and Hunter, Susan W. and Miao, Wenxin and Tirona, Rommel G.",
volume="24",
number="3",
pages="237-250",
abstract="BACKGROUND: Medication review is essential in managing adverse drug reactions and improving drug safety in older adults. This systematic review evaluated medication review's role as a single intervention or combined with other interventions in preventing fall-related injuries in older adults. <br><br>METHODS: Electronic databases search was conducted in PubMed, EMBASE, Scopus, and CINAHL. Two reviewers screened titles and abstracts, reviewed full texts, and performed data extraction and risk of bias assessment. Meta-analyses were conducted on studies with similar participants, interventions, outcomes or settings. <br><br>RESULTS: Fourteen randomized, controlled studies were included. The pooled results indicated that medication review as a stand-alone intervention was effective in preventing fall-related injuries in community-dwelling older adults (Risk Difference [RD] = -0.06, 95% CI: [-0.11, -0.00], I(2) = 61%, p =.04). Medication review also had a positive impact on decreasing the risk of fall-related fractures (RD = -0.02, 95% CI: [-0.04, -0.01], I(2) = 0%, p =.01). <br><br>DISCUSSION: This systematic review and meta-analysis has demonstrated that medication review is effective in preventing fall-related injuries in general, and fractures specifically, in community-dwelling older adults. Future investigations focusing on the process of performing medication review will further inform fall-related injury prevention for older adults.<p /> <p>Language: en</p>",
language="en",
issn="1925-8348",
doi="10.5770/cgj.24.478",
url="http://dx.doi.org/10.5770/cgj.24.478"
}