@article{ref1,
title="A role for the cortex in sleep-wake regulation",
journal="Nature neuroscience",
year="2021",
author="Krone, Lukas B. and Yamagata, Tomoko and Blanco-Duque, Cristina and Guillaumin, Mathilde C. C. and Kahn, Martin C. and van der Vinne, Vincent and McKillop, Laura E. and Tam, Shu K. E. and Peirson, Stuart N. and Akerman, Colin J. and Hoerder-Suabedissen, Anna and Molnár, Zoltán and Vyazovskiy, Vladyslav V.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="Cortical and subcortical circuitry are thought to play distinct roles in the generation of sleep oscillations and global state control, respectively. Here we silenced a subset of neocortical layer 5 pyramidal and archicortical dentate gyrus granule cells in male mice by ablating SNAP25. This markedly increased wakefulness and reduced rebound of electroencephalographic slow-wave activity after sleep deprivation, suggesting a role for the cortex in both vigilance state control and sleep homeostasis.<p /> <p>Language: en</p>",
language="en",
issn="1097-6256",
doi="10.1038/s41593-021-00894-6",
url="http://dx.doi.org/10.1038/s41593-021-00894-6"
}