@article{ref1,
title=""Going Backward": Effects of age and fatigue on posterior-directed falls in Parkinson disease",
journal="NeuroRehabilitation",
year="2021",
author="Papa, Evan V. and Patterson, Rita M. and Bugnariu, Nicoleta",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="BACKGROUND: Nearly half of persons with Parkinson disease (PD) report fatigue as a factor in their fall history. However, it is unknown whether these self-reported falls are caused by a sensation of fatigue or performance fatigue. <br><br>OBJECTIVE: We sought to investigate the influences of performance fatigue and age on postural control in persons with PD. <br><br>METHODS: Individuals with PD (n = 14) underwent postural control assessments before (T0) and immediately after (T1) fatiguing exercise. Biomechanical data were gathered on participants completing a treadmill-induced, posterior-directed fall. Performance fatigue was produced using lower extremity resistance exercise on an isokinetic ergometer. Repeated measures ANCOVAs were used with age as a covariate to determine the effects of performance fatigue on biomechanical variables. <br><br>RESULTS: After adjustment for age, there was a statistically significant difference in peak center of pressure (COP) latency during the support phase of recovery. Pairwise comparisons demonstrated a decrease in peak ankle displacement from T0 to T1. Age was also found to be significantly related to reaction time and peak knee displacement while participants were fatigued. <br><br>CONCLUSIONS: The decreased peak COP latency, along with decreased ankle angular displacement, suggest that persons with PD adopt a stiffening strategy in response to backward directed falls. Postural stiffening is not uncommon in persons with PD and could be a risk factor for falls. Older individuals with PD demonstrate slower mobility scores and decreased reaction times in the setting of fatigue, suggesting a combined effect of the aging and fatigue processes.<p /> <p>Language: en</p>",
language="en",
issn="1053-8135",
doi="10.3233/NRE-210040",
url="http://dx.doi.org/10.3233/NRE-210040"
}