
@article{ref1,
title="Neuroinflammation and hypothalamo-pituitary dysfunction: focus of traumatic brain injury",
journal="International journal of molecular sciences",
year="2021",
author="Mele, Chiara and Pingue, Valeria and Caputo, Marina and Zavattaro, Marco and Pagano, Loredana and Prodam, Flavia and Nardone, Antonio and Aimaretti, Gianluca and Marzullo, Paolo",
volume="22",
number="5",
pages="-",
abstract="The incidence of traumatic brain injury (TBI) has increased over the last years with an important impact on public health. Many preclinical and clinical studies identified multiple and heterogeneous TBI-related pathophysiological mechanisms that are responsible for functional, cognitive, and behavioral alterations. Recent evidence has suggested that post-TBI neuroinflammation is responsible for several long-term clinical consequences, including hypopituitarism. This review aims to summarize current evidence on TBI-induced neuroinflammation and its potential role in determining hypothalamic-pituitary dysfunctions.<p /> <p>Language: en</p>",
language="en",
issn="1661-6596",
doi="10.3390/ijms22052686",
url="http://dx.doi.org/10.3390/ijms22052686"
}