
@article{ref1,
title="A patient-specific fluid-structure interaction model of the cerebrovascular damage in relation to traumatic brain injury",
journal="Trauma (Sage)",
year="2021",
author="Razaghi, Reza and Biglari, Hasan and Karimi, Alireza",
volume="23",
number="1",
pages="33-43",
abstract="BackgroundThere is a lack of knowledge on the magnitudes of the biomechanical stresses and deformations occurring in the cerebral arterial wall after traumatic brain injury (TBI). Experimental techniques are unable to calculate the stresses and deformations in the cerebral arterial wall after TBI; therefore, the application of numerical simulations, such as finite element modeling, is preferred.<br><br>METHODSThis study was aimed to calculate the stresses and deformations as well as the alteration in the pressure and velocity of the blood in the cerebrovascular artery using a fluid?structure interaction model.<br><br>RESULTSThe results revealed considerable increase in the pressure and velocity of the blood which might lead to cerebrovascular damage followed by hemorrhage. The arterial wall showed the highest deformation of 0.047?mm in the X direction which was higher than that in the Y (0.035?0.050?mm) and Z (0.019?0.030?mm) directions.<br><br>CONCLUSIONSThese results have implications not only for the understanding of the stresses and deformations in the cerebral artery because of TBI, but also for providing a comprehensive knowledge for biomechanical and medical experts in regard to thresholds of cerebrovascular damage for use in establishing preventive and/or treatment methods.<p /> <p>Language: en</p>",
language="en",
issn="1460-4086",
doi="10.1177/1460408620921729",
url="http://dx.doi.org/10.1177/1460408620921729"
}