@article{ref1,
title="Prognostic factors for recovery of health status after injury: a prospective multicentre cohort study",
journal="BMJ open",
year="2021",
author="de Jongh, Mariska A. C. and de Munter, Leonie and Steyerberg, Ewout W. and Havermans, Roos J. M. and Polinder, Suzanne",
volume="11",
number="1",
pages="e038707-e038707",
abstract="OBJECTIVES: To determine prognostic factors for health status and recovery patterns during the first 2 years after injury in the clinical trauma population. <br><br>DESIGN: A  prospective longitudinal cohort study. SETTING: Ten participating hospitals in  Brabant, the Netherlands. PARTICIPANTS: Injured adult patients admitted to a  hospital between August 2015 and November 2016 were followed: 4883 (50%) patients  participated. MAIN OUTCOME MEASURES: Primary outcome was health status, measured  with the EuroQol-5-dimensions-3-levels (EQ-5D), including a cognition item and the  EuroQol Visual Analogue Scale. Health status was collected at 1 week, 1, 3, 6, 12  and 24 months after injury. Potential prognostic factors were based on literature  and clinical experience (eg, age, sex, pre-injury frailty (Groningen Frailty Index),  pre-injury EQ-5D). <br><br>RESULTS: Health status increased mainly during the first 6 months  after injury with a mean EQ-5D utility score at 1 week of 0.49 and 0.79 at 24  months. The dimensions mobility, pain/discomfort and usual activities improved up to  2 years after injury. Lower pre-injury health status, frailty and longer length of  stay at the hospital were important prognostic factors for poor recovery. Spine  injury, lower and upper extremity injury showed to be prognostic factors for  problems after injury. Traumatic brain injury was a prognostic factor for cognitive  problems. <br><br>CONCLUSION: This study contributes to the increase in knowledge of health  recovery after injury. It could be a starting point to develop prediction models for  specific injury classifications and implementation of personalised medicine. TRIAL  REGISTRATION NUMBER: NCT02508675.<p /> <p>Language: en</p>",
language="en",
issn="2044-6055",
doi="10.1136/bmjopen-2020-038707",
url="http://dx.doi.org/10.1136/bmjopen-2020-038707"
}