@article{ref1,
title="Dual-task costs of quantitative gait parameters while walking and turning in people with Parkinson's disease: beyond gait speed",
journal="Journal of Parkinson's disease",
year="2020",
author="Vitório, Rodrigo and Hasegawa, Naoya and Carlson-Kuhta, Patricia and Nutt, John G. and Horak, Fay Bahling and Mancini, Martina and Shah, Vrutangkumar V.",
volume="ePub",
number="ePub",
pages="ePub-ePub",
abstract="BACKGROUND: There is a lack of recommendations for selecting the most appropriate gait measures of Parkinson's disease (PD)-specific dual-task costs to use in  clinical practice and research. <br><br>OBJECTIVE: We aimed to identify measures of  dual-task costs of gait and turning that best discriminate performance in people  with PD from healthy individuals. We also investigated the relationship between the  most discriminative measures of dual-task costs of gait and turning with disease  severity and disease duration. <br><br>METHODS: People with mild-to-moderate PD (n = 144)  and age-matched healthy individuals (n = 79) wore 8 inertial sensors while walking  under single and dual-task (reciting every other letter of the alphabet) conditions. Outcome measures included 26 objective measures within four gait domains  (upper/lower body, turning and variability). The area under the curve (AUC) from the  receiver-operator characteristic plot was calculated to compare discriminative  ability of dual-task costs on gait across outcome measures. <br><br>RESULTS: PD-specific,  dual-task interference was identified for arm range of motion, foot strike angle,  turn velocity and turn duration. Arm range of motion (AUC = 0.73) and foot strike  angle (AUC = 0.68) had the largest AUCs across dual-task costs measures and they  were associated with disease severity and/or disease duration. In contrast, the most  commonly used dual-task gait measure, gait speed, showed an AUC of only 0.54. <br><br>CONCLUSION: Findings suggest that people with PD rely more than healthy individuals  on executive-attentional resources to control arm swing, foot strike, and turning,  but not gait speed. The dual-task costs of arm range of motion best discriminated  people with PD from healthy individuals.<p /> <p>Language: en</p>",
language="en",
issn="1877-7171",
doi="10.3233/JPD-202289",
url="http://dx.doi.org/10.3233/JPD-202289"
}